Medicine Identification New Database (MIND): A quick, simple and accurate tool for the identification of unlabeled medication in hospital pharmacy.
Medication errors are one of the most important problem that significantly influence patient safety in health care. A very common source of medication errors is the mix-up of „Look-Alike and Sound-Alike“ (LASA) medication.
LASA medications are medications that are visually similar in physical appearance or packaging or that have names with spelling similarities and/or similar phonetics. LASA medication confusions by patients, physicians and pharmacists is a major concern which can lead to serious health risks for the patients.
Scientists of Groupement Hospitalier Centre Edouard Herriot / Lyon, France* have developed a new tool named Medicine Identification New Database (MIND) to quickly and accurately identify unlabeled medication even by untrained individuals. This is especially important after the medication has been removed from initial packaging and blister and then been filled in unlabeled dispensers for the various patients.
MIND is a 3-moduled screening process of identifying (1) commercialized information (manufacturer, CAS number and active pharmaceutical ingredient), (2) organoleptic properties (type, shape, color, size, weight) and (3) collecting an ATR-FTIR spectrum of the medication to precisely identify the medication.
*Study performed by Elsa Reallon, Chloé Marchand, Anne-Laure Yaillan, Samira Filali, Camille Merienne, Carole Paillet, Christine Pivot, Fabrice Pirot, Anne-Laure Yaillan
Service Pharmaceutique, Groupement Hospitalier Centre Edouard Herriot, Place d’Arsonval, F-69437 5 Lyon Cedex 03, France.
The backbone of the ATR-FTIR module is a reference spectra database containing more than 500 entries with extensive sample information. The spectra in this database were measured in the hospital laboratories by scientific personnel and then transferred to the S.T. Japan-Europe. S.T.Japan-Europe issued this database in all the various data formats so that it can be used with most instruments/software packages in the market. (Pharmaceutical Tablets and Capsules Database L30030, S.T. Japan-Europe, D - 50937 Köln, Germany).
The simplicity of the approach combining organoleptic identification criteria with the accuracy of physical and spectral characterization with ATR-FTIR confirmed the potential of MIND as a suitable tool for the quick, simple and accurate identification of unlabeled unitary medication in health care.
Additionally, the combination of these three modules reliably discriminate, characterize and identify counterfeit medication and also medication questioned for their physico-chemical integrity and stability after long-storage in various conditions of temperature and humidity.
Published in Spectrocopy Europe - click here to read the article.
The new databases, ATR-FTIR and Raman, contain a great variety of well-defined synthetic polymers and polymers commonly found in commercial and industrial products worldwide.
This includes non-biodegradable plastics, packaging materials, synthetic polymer-based materials and other substances relevant for the microplastics analysis.
The databases are compatible with the software of all major instrument manufacturers.
They can be used for single-particle identification but also for methods such as chemical imaging based on the automated analysis software of your specific instrument.
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The Gesellschaft Deutscher Chemiker (GDCh) is the largest chemical society in continental Europe with members from academe, education, industry and other areas.
The GDCh supports chemistry in teaching, research and application and promotes the understanding of chemistry in the public.
GDCh's division of Analytical Chemistry quarterly issues a bulletin with lots of interesting articles. In the last edition of 2019 a really great article about S.T.Japan-Europe GmbH was published!
We thank the GDCh very much and are happy to share this article with you.
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November 11-13, 2020
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